Vithamine B9

Lisebelisoa tse sebetsang le litlamorao 'meleng

Melemo ea vithamine B9 bakeng sa 'mele:

• e ama tsela ea bokhachane bo phetseng hantle le kholo e nepahetseng ea lesea le ka popelong: folic acid e thibela kholo ea bofokoli tsamaisong ea methapo ea lesea, boima ba 'mele, pelehi pele ho nako,' me sena se etsahala methating ea pele ea bokhachane.
• antidepressant: folic acid e nahanoa hore e thusa ho sebetsana le khatello ea maikutlo le ho ntlafatsa boiketlo ba maikutlo.
• e thusa ho metabolism ea protheine.
• Khahlanong le: Vithamine B9 e nkuoa e le antioxidant e matla e thusang ho ntša chefo 'meleng le ho ntlafatsa boemo ba letlalo.
• Ho boloka bophelo bo botle ba pelo: Ho sebelisa folic acid ho theola maemo a mali a homocysteine, a ka phahamisoang mme a ka u beha kotsing ea lefu la pelo. Ho feta moo, ho rarahana ha livithamini tsa B, ho kenyeletsang folic acid, ho fokotsa menyetla ea kholo.
• Ho fokotsa kotsi ea mofets'e: Ho na le bopaki ba hore ho ja lijo tse sa lekanang ho amana le kholo ea mofets'e oa basali.

Folic acid metabolism 'meleng

Folate e sebetsa e le coenzyme ho nucleic acid synthesis le amino acid metabolism. Hang ha e le 'meleng, mefuta e fapaneng ea phepo e haelloa ke hydrolyzed ho ea ka monoglutamate ka maleng pele e kenoa ke lintho tse tsamaisang lipalangoang ka lehare la mucous. Pele ho kenoa ka phallo ea mali, mofuta oa monoglutamate o fokotsoa ho ba tetrahydrofolate (THF) ebe o fetoloa foromo ea methyl kapa formyl. Mofuta o ka sehloohong oa folate ka mali a mali ke 5-methyl-THF. Folic acid e ka fumanoa e sa fetohe maling (folic acid e sa kopaneng), empa ha ho tsejoe hore na foromo ena e na le ts'ebetso efe kapa efe ea bioloji.

Bakeng sa folate le li-coenzymes tsa eona ho tšela lera la sele, bajari ba khethehileng ba hlokahala. Tsena li kenyelletsa ho fokotsa folate transporter (RFC), proton coupled folate transporter (PCFT), le folate protein receptor, FRα le FRβ. Folate homeostasis e tšehetsoa ke ho ata ha batho ba tsamaisang batho ba bangata, leha palo ea bona le bohlokoa ba tsona li fapana ka lisele tse fapaneng tsa 'mele. PCFT e bapala karolo ea bohlokoa ho feng transplantation hobane liphetoho tse amang PCFT ea lefutso li baka lefutso la malabsorption. PCFT e nang le phoso e boetse e fella ka ho senyeha ha lipalangoang tsa folate bokong. FRa le RFC le tsona li bohlokoa bakeng sa ho tsamaisa folate kahare ho mokoallo o lipakeng tsa tsamaiso ea potoloho ea mali le tsamaiso ea methapo e bohareng. Folate e bohlokoa molemong oa kholo e nepahetseng ea lesea le ka popelong. Lefu la placenta le tsejoa e le lona le ikarabellang bakeng sa ho lokolloa ha folate ho lesea, e leng se hlahisang likarolo tse phahameng tsa folate ho lesea ho feta ho mme. Mefuta eohle e meraro ea li-receptor e amahanngoa le ho tsamaisa folate ho pholletsa le placenta nakong ea bokhachane.

Ho sebelisana le li-micronutrients tse ling

Folate le hammoho li theha e 'ngoe ea li-micronutrient tse matla ka ho fetisisa. Tšebelisano ea bona e tšehetsa tse ling tsa mekhoa ea bohlokoa ka ho fetisisa ea karohano ea lisele le ho ikatisa. Ho feta moo, ba kopane hammoho ho kenya letsoho metabolism ea homocysteine. Ho sa tsotellehe taba ea hore livithamine tsena tse peli li ka fumanoa ka tlhaho ho tloha mefuta e 'meli e fapaneng ea lijo (vithamine B12 - ho tloha lihlahisoa tsa liphoofolo: nama, sebete, mahe, lebese le vithamine B9 - ho tloha meroho e makhasi, linaoa), kamano ea bona ke ea bohlokoa haholo. bakeng sa mmele. Li sebetsa e le li-cofactors ha ho etsoa methionine ho tloha homocysteine. Haeba synthesis e sa etsahale, joale boemo ba homocysteine ​​​​e ka phahama, boo hangata bo amanang le kotsi ea lefu la pelo le stroke.

Tšebelisano ea bohlokoa ea metabolic ho vithamine B9 e etsahala le riboflavin (). Ea morao-rao ke selelekela sa coenzyme e amehang ho folate metabolism. E fetola folate ho sebopeho sa eona se sebetsang, 5-methyltetrahydrofolate.

e ka fokotsa tšenyo ea tlhaho ea folate coenzymes le tlatsetso ea folic acid ka mpeng mme ka hona ea ntlafatsa foa ea bioavailability.

Mefuta e metle ea lijo tse nang le vithamine B9

Vithamine B9 e na le thuso ho kopana le livithamini tse ling tsa B.

Ka mohlala, ka salate e nang le khale, peo ea soneblomo, feta, harese, eiee e khubelu, li-chickpea, avocado le moaparo oa sirilamunu. Salate e joalo e tla fa 'mele livithamini B3, B6, B7, B2, B12, B5, B9.

Kakaretso e ntle ea lijo tsa hoseng kapa tsa mots'eare ke sandwich e entsoeng ka bohobe bo felletseng ba koro, saalmon e tsubang, asparagase le mahe a ts'oetsoeng. Sejana sena se na le livithamini tse kang B3 le B12, B2, B1 le B9.

Lijo ke mohloli o motle ka ho fetisisa oa livithamini. Ka hona, monyetla oa ho nka livithamini ka mokhoa oa meriana o lokela ho tsotelloa haeba ho na le lintlha tse loketseng. Ho na le bopaki ba hore litokisetso tsa livithamini haeba li sebelisoa hampe ha li rue molemo feela, empa li ka lematsa le 'mele.

Sebelisa meriana ea molao

Boimana

Folic acid e sebelisoa merianeng ka mabaka a mangata. Pele, e laeloa bakhachane le ba itokisetsang kemolo. Khōlo le kholo ea lesea le ka ponahalo li khetholloa ka ho arohana ha sele ka mafolofolo. Litekanyo tse lekaneng tsa folate li bohlokoa bakeng sa synthesis ea DNA le RNA. Ka lebaka la khaello ea folic acid, lipakeng tsa matsatsi a 21 le 27 kamora kemaro, lefu le bitsoang sekoli sa methapo ea methapo… Ka molao, nakong ena, mosali ha a tsebe hore o imme mme a ke ke a nka mehato e nepahetseng ka ho eketsa palo ea batho ba lijong. Lefu lena le lebisa liphellong tse 'maloa tse sa rateheng tsa lesea le ka pōpelong - tšenyo ea boko, encephalocele, liso tsa mokokotlo.

Ho senyeha ha pelo ea Congenital ke sesosa se ka sehloohong sa lefu ho bana ebile ho ka lebisa lefung ha motho a le moholo. Ho latela Registry ea Europe ea Congenital Anomalies le Gemini, ho ja bonyane 400 mcg ea folic acid ka letsatsi khoeling e le 'ngoe pele ho kemolo le libeke tse 8 kamora moo ho fokotsitse menyetla ea ho holofala ha pelo ka liperesente tse 18.

Mefuta ea folate ea bakhachane e ka susumetsa kotsi ea ho ba le tlhekefetso ea tlhaho ea tlhaho ea tlhaho. Patlisiso ea Norway e bonts'itse hore ho nka tlatsetso ea vithamine e nang le bonyane mcg ea folate ho fokotseng kotsi ea ho phatloha ha mahalapa ka 400%.

Boima ba 'mele bo tlase bo amahanngoa le kotsi e eketsehileng ea lefu selemong sa pele sa bophelo mme e ka ama maemo a bophelo bo botle ha motho a le moholo. Tlhahlobo ea morao-rao e hlophisitsoeng le tlhahlobo ea litlhahlobo tsa lithuto tse robeli tse laoloang li bonts'a botsoalle bo nepahetseng lipakeng tsa ho ja le boima ba 'mele.

Litekanyo tse phahameng tsa mali tsa homocysteine ​​le tsona li amahanngoa le keketseho ea ho senyeheloa ke mpa le mathata a mang a bokhachane, ho kenyeletsoa preeclampsia le ho senyeha ha menoana. Phuputso e kholo ea morao-rao e bonts'itse hore maemo a plasma homocysteine ​​ho basali a amme ka kotloloho boteng ba litlamorao tse bohloko tsa bokhachane le mathata, ho kenyeletsoa preeclampsia, pelehi pelehi le boima ba 'mele bo tlase haholo. Taolo ea homocysteine ​​le eona e etsahala ka ho nka karolo ea folic acid.

Kahoo, ho bohlale ho nka folic acid, tlasa taolo ea ngaka, nakong eohle ea bokhachane, le kamora hore tube ea methapo e koaloe, ho fokotsa kotsi ea mathata a mang nakong ea bokhachane. Ho feta moo, lithuto tsa morao-rao ha li fumane bopaki ba kamano pakeng tsa ho noa folate nakong ea bokhachane le litlamorao tse mpe tsa bophelo bo botle ho bana, haholoholo nts'etsopele ea I.

Maloetse a pelo

Liphuputso tse fetang 80 li bonts'a hore le maemo a phahameng a mali a homocysteine ​​a eketsa kotsi ea lefu la pelo. Mechini eo homocysteine ​​e ka eketsang kotsi ea lefu la methapo e ntse e le taba ea lipatlisiso tse ngata, empa e kanna ea kenyelletsa litlamorao tse mpe tsa homocysteine ​​mabapi le ho hoama ha mali, vasodilation ea arterial le ho tenya ha marako a methapo. Lijo tse nang le boleng bo phahameng li 'nile tsa amahanngoa le kotsi e fokotsehileng ea lefu la pelo, ho kenyelletsa le myocardial (lefu la pelo) le stroke. Phuputso e entsoeng ho banna ba 1980 naheng ea Finland ka nako ea lilemo tse 10 e fumane hore ba jang palo e phahameng ea lijo ba na le kotsi e tlase ea 55% ea lefu la tšohanyetso la pelo ha ba bapisoa le ba jang folate e nyane haholo. Har'a livithamini tse tharo tsa B tse laolang mahloriso a homocysteine, folate e bontšitsoe e na le phello e kholo ho theoleng likhahla tsa basal, ha feela ho se na khaello ea vithamine B12 kapa vithamine B6. Ho fumanoe keketseho ea batho ba kenang folate ho tsoa lijong tse nang le folate kapa li-supplements tse fokotsang likhakanyo tsa homocysteine.

Leha ho na le phehisano mabapi le karolo ea ho theola homocysteine ​​ho thibela lefu la pelo, lithuto tse 'maloa li hlahlobile litlamorao tsa nts'etsopele ea folate supplementation, e tsejoang e le kotsi ea lefu la vascular. Le ha liteko tsa morao-rao li sa bonts'a hore folate e sireletsa 'mele ka kotloloho, ho ja lijo tse fokolang haholo ke kotsi e tsebahalang ea lefu la pelo.

Cancer

Kankere e nahanoa hore e bakoa ke tšenyo ea DNA ka lebaka la lits'ebetso tse ngata haholo tsa tokiso ea DNA, kapa ka polelo e fosahetseng ea liphatsa tsa lefutso. Ka lebaka la karolo ea bohlokoa ea folate ho DNA le RNA synthesis, ho ka etsahala hore ho noa vithamine B9 ho sa tlatselletseng ho baka ho se tsitse ha genome le likoli tsa chromosome tse atisang ho amahanngoa le nts'etsopele ea mofetše. Ka ho khetheha, ho pheta-pheta le ho lokisoa ha DNA ho bohlokoa ho boloka genome, 'me ho haella ha li-nucleotide tse bakoang ke khaello ea folate ho ka baka ho se tsitse ha genome le phetoho ea DNA. Folate e boetse e laola potoloho ea homocysteine ​​/ methionine le S-adenosylmethionine, mofani oa methyl bakeng sa liphetoho tsa methylation. Kahoo, khaello ea folate e ka senya DNA le protheine methylation mme ea fetola polelo ea liphatsa tsa lefutso tse amehang ho lokisa DNA, karohano ea lisele le lefu. Global DNA hypomethylation, e leng letšoao le tloaelehileng la mofetše, e baka ho se tsitse ha genome le ho robeha ha chromosomal.

Ho ja bonyane litholoana le meroho e mehlano ka letsatsi ho amahanngoa le ho fokotseha ha liketsahalo tsa mofetše kajeno. Litholoana le meroho ke mehloli e metle ea folate, e ka bang le seabo ho litla-morao tsa bona tse thibelang kankere.

Lefu la Alzheimer le 'dementia'

Lefu la Alzheimer ke mofuta o tloaelehileng haholo. Phuputso e 'ngoe e fumane botsoalle lipakeng tsa keketseho ea ho ja litholoana le meroho e ruileng ka folate le ho fokotsa kotsi ea' dementia 'ho basali.

Ka lebaka la karolo ea eona ho kopaneng li-acid tsa nucleic le ho fana ka methyl e lekaneng bakeng sa liphetoho tsa methylation, folate e ama kholo e tloaelehileng le ts'ebetso ea boko, eseng feela nakong ea bokhachane le kamora ho beleha, empa hape le bophelong. Phuputsong e le 'ngoe ea basali ba baholo, bakuli ba Alzheimer ba ne ba na le maemo a phahameng haholo a homocysteine ​​le maemo a tlase a mali ha a bapisoa le batho ba phetseng hantle. Ntle le moo, ramahlale o fihletse qeto ea hore litekanyetso tsa nako e telele tsa mali, ho fapana le ts'ebeliso ea morao-rao, li na le boikarabello ba ho thibela 'dementia'. Phuputso e entsoeng ka lilemo tse peli, e laoloang ke "placebo" e laoloang ke "placebo" ho bakuli ba seng ba tsofetse ba 168 ba nang le ts'oaetso e bonolo ea ts'ebeliso ea kelello e fumane melemo ea ho noa 800 mcg folate, 500 mcg vithamine B12 le vithamine B20 ea 6 mg. Atrophy ea libaka tse ling tsa boko bo anngoeng ke lefu la Alzheimer e ile ea bonoa ho batho ka bomong ba lihlopha tsena ka bobeli, mme atrophy ena e ne e amana le ho fokotseha ha mohopolo; leha ho le joalo, sehlopha se alafiloeng ka livithamini tsa B se ile sa ba le tahlehelo e tlase ea bohlooho ha se bapisoa le sehlopha sa placebo (0,5% ha se bapisoa le 3,7%). Phello e molemo ka ho fetisisa e fumanoe ho bakuli ba nang le likhakanyo tse phahameng tsa homocysteine, ho fana ka maikutlo a bohlokoa ba ho fokotsa ho potoloha ha homocysteine ​​ho thibela ho fokotseha ha kelello le 'dementia'. Leha e na le phello e ts'episang, tlatsetso ea vithamine ea B e hloka ho hlahlojoa le ho feta lithutong tse kholo tse lekolang sephetho sa nako e telele, joalo ka ketsahalo ea lefu la Alzheimer's.

ho tepella maikutlo

Maemo a tlase a folate a hokahantsoe le khatello ea maikutlo le karabelo e mpe ho li-anti-depressing. Phuputso ea haufinyane ea batho ba 2 ba lilemo li 988 ho isa ho 1 United States e fumane hore li-serum le lisele tse khubelu tsa lisele tsa mali li ne li le tlase haholo ho batho ba tepelletseng maikutlo ho feta ba neng ba e-s'o ka ba tepella maikutlo. Liphuputso ho banna le basali ba 39 ba fumanoeng ba na le lefu la ho tepella maikutlo li fumane hore ke bakuli ba 52 ho ba 1 ba nang le maemo a tlase a arabetseng kalafo ea khatello ea maikutlo, ha ba bapisoa le bakuli ba 14 ho ba 17 ba nang le maemo a tloaelehileng a folate.

Le ha folic acid e tlatsetsang e sa hlahisoe e le sebaka sa kalafo e tloahelehileng ea ho imeloa kelellong, e kanna ea ba molemo joaloka motlatsi. Phuputsong ea UK, bakuli ba 127 ba tepelletseng maikutlo ba ile ba khethoa ho nka 500 mcg ea folate kapa placebo ntle le 20 mg ea fluoxetine (antidepressant) letsatsi le letsatsi bakeng sa libeke tse 10. Le ha litlamorao ho banna e ne e se tsa bohlokoa lipalo, basali ba fumaneng fluoxetine hammoho le folic acid ba sebelitse hantle haholo ho feta ba fumaneng fluoxetine hammoho le placebo. Bangoli ba phuputso ba fihletse qeto ea hore lipale "li ka ba le karolo e ka thusang ho alafa khatello ea maikutlo."

Mefuta ea litekanyo tsa vithamine B9

Mofuta o tloaelehileng haholo oa folic acid ke matlapa. Tekanyo ea vithamine e ka fapana, ho latela sepheo sa moriana. Li-vithamine bakeng sa bakhachane, litekanyo tse atileng haholo ke 400 mcg, hobane chelete ena e nkuoa e lekane bakeng sa kholo e phetseng hantle ea lesea. Hangata folic acid e kenyelelitsoe litsing tsa vithamine hammoho le livithamini tse ling tsa B. Meaho e joalo e ka ba ka sebopeho sa matlapa, ka sebopeho sa lipoleiti tse hlafunang, matlapa a qhibilihang hammoho le liente.

Ho theola maemo a mali a homocysteine, hangata 200 mcg ho 15 mg ea folate e fanoa ka letsatsi. Ha u phekola khatello ea maikutlo, noa vithamine ea 200 ho isa ho 500 mcg ka letsatsi, ntle le kalafo ea mantlha. Tekanyo efe kapa efe e tlameha ho laeloa ke ngaka e eang teng.

Folic acid meriana ea setso

Lingaka tsa setso joalo ka lingaka tsa bongaka ba setso li lemoha bohlokoa ba asiti ea folic ho basali, haholo basali ba nang le bakhachane, le karolo ea eona ea ho thibela lefu la pelo le phokolo ea mali.

Folic acid e fumanoa, ka mohlala, ka. Litholoana tsa eona li buelloa bakeng sa mafu a liphio, sebete, methapo ea mali le pelo. Ntle le folate, fragole li boetse li ruile ka li-tannin, potasiamo, tšepe, phosphorus, cobalt. Bakeng sa bongaka, litholoana, makhasi le metso li sebelisoa.

Folate, hammoho le oli ea bohlokoa, vithamine C, carotene, flavonoids le tocopherol, li fumaneha peo. Semela ka boeona se na le phello ea bile le diuretic, e imolla li-spasms mme e hloekisa 'mele. Infusion le decoction ea peo e thusa ka ho ruruha ha lera la mucous la pampiri ea ho ntša metsi. Ho phaella moo, infusion ea parsley e laeloa bakeng sa mali a tsoang ka popelong.

Mohloli o ruileng oa folic acid meriana ea setso e nkuoa. Li na le metsi a etsang liphesente tse 65 ho isa ho tse 85, tsoekere e etsang liphesente tse 10 ho isa ho 33, le lintho tse ngata tse nang le thuso - liasiti tse fapaneng, li-tannin, potasiamo, magnesium, calcium, manganese, cobalt, iron, livithamini B1, B2, B6, B9, A, C, K, P, PP, li-enzyme.

Patlisiso ea morao-rao ea mahlale a vithamine B9

• Ho sebelisa tekanyetso e phahameng ea folic acid ha ho ame kotsi ea ho ba le preeclampsia. Ke boemo bo tebileng ba bongaka bo khetholloang ke nts'etsopele ea khatello e phahameng ea mali nakong ea bokhachane le mathata a mang. Boemo bona bo kotsi ho 'm'a le ho ngoana. Ho 'nile ha boleloa pejana hore tekanyetso e phahameng ea folate e ka fokotsa menyetla ea ho ba le folate ho basali ba nang le ts'oaetso ea lefu lena. Tsena li kenyelletsa ba nang le khatello e phahameng ea mali khafetsa; basali ba tšoeroeng ke kapa; o imme mafahla; hammoho le ba nang le preeclampsia nakong ea bokhachane bo fetileng. Phuputso e ne e kenyelletsa basali ba fetang likete tse 2 ba neng ba le moimana lipakeng tsa libeke tse 8 le 16. Ho fumanoe hore ho nka 4 mg ea folic acid letsatsi le letsatsi ha ho ame kotsi ea ho ba le lefu lena ha le bapisoa le ba nkileng placebo ntle le tekanyetso ea 1 mg ea folate (14,8% ea linyeoe le linyeoe tse 13,5%) , ka ho latellana). Leha ho le joalo, lingaka li ntse li khothaletsa ho nka tekanyetso e tlase ea folate pele le nakong ea bokhachane ho thibela nts'etsopele ea mafu a tlhaho.
• Bo-rasaense ba Ireland ba fihletse qeto ea hore palo e kholo ea batho ba fetang lilemo tsa 50 ba haelloa ke vithamine B12 (1 ho batho ba 8) mme ba folate (1 ho batho ba 7). Tekanyo ea khaello e fapana le mokhoa oa bophelo, bophelo bo botle le boemo ba phepo e nepahetseng. Li-vithamine ka bobeli li bohlokoa molemong oa tsamaiso ea methapo, boko, tlhahiso ea lisele tse khubelu tsa mali le karohano ea DNA. Hape ho fumanoe hore liperesente tsa khaello ea folate e eketseha ka lilemo - ho tloha ho 14% har'a batho ba lilemo li 50-60, ho isa ho 23% ho ba fetang lilemo tse 80. Hangata e ne e fumanoa ho batho ba tsubang, batho ba batenya le ba lulang ba le bang. Ho haella ha vithamine B12 ho ne ho atile haholo ho ba tsubang (14%), ba lula ba le bang (14,3%), le ho batho ba tsoang maemong a tlase a moruo.
• Bo-rasaense ba Borithane ba tsitlallela ho ruisa phofo le lijo tse ling ka folic acid. Ho ea ka bangoli ba phuputso, letsatsi le leng le le leng Borithane, ka karolelano, basali ba babeli ba qobelloa ho emisa ho ima ka lebaka la sekoli sa methapo ea kutlo, 'me masea a mabeli a hlaha a e-na le lefu lena beke e' ngoe le e 'ngoe. Brithani ke e 'ngoe ea linaha tseo ho tsona qhobosheane ea setso e seng ntho e tloaelehileng, ho fapana le United States le linaha tse ling. Moprofesa Joan Morris o re: “Hoja Brithani e ne e ngolisitse semolao ka molao ka 1998, joalo ka Amerika, likholofalo tsa tsoalo tse ka bang 2007 li ka be li ile tsa qojoa ke 3000.

Sebelisa cosmetology

Folic acid e bapala karolo ea bohlokoa haholo ho eona. E na le li-antioxidants tse fokotsang tšebetso ea lits'ebetso tsa oxidative le ho fokotsa li-radicals tsa mahala tse fumanehang tikolohong. Lisebelisoa tsa tlhokomelo ea letlalo ea folic acid le tsona li thusa ho boloka metsi a letlalo ka ho matlafatsa mokoallo oa letlalo. Sena se tšoasa mongobo mme se fokotsa ho oma.

Ka litlolo, lihlahisoa tsa folate hangata li kenyelelitsoe ho litlolo tse mongobo le litlolo, tseo, ha li sebelisoa ka holimo, li ka thusang ho ntlafatsa boleng ba kakaretso le ponahalo ea letlalo.

Ts'ebeliso ea mehlape

Ho haelloa ke asiti ea folic ho fumanoe ka liteko mefuteng e mengata ea liphoofolo, e bonts'itsoeng ka mokhoa oa phokolo ea mali, ho fokotseha ha palo ea leukocyte. Haholo-holo lisele tse nang le sekhahla se phahameng sa kholo ea lisele kapa nchafatso ea lisele lia ameha, joalo ka lesela la epithelial la pampiri ea meno, epidermis le moko oa masapo. Ho lintja le likatse, khaello ea mali khafetsa e amahanngoa le khaello ea folate e bakoang ke mala a mala a malabsorption, khaello ea phepo e nepahetseng, bahanyetsi ba folate, kapa litlhoko tse eketsehileng tsa folate ka lebaka la tahlehelo ea mali kapa hemolysis. Bakeng sa liphoofolo tse ling tse kang likolobe, litšoene le likolobe, ho ba le folate e lekaneng lijong ho bohlokoa. Liphoofolong tse ling, ho kenyeletsoa lintja, likatse le likhoto, asiti ea folic e hlahisoang ke mala a microflora hangata e lekane ho fihlela litlhoko. Ka hona, matšoao a khaello a ka hlaha haeba sebolaya-mafu sa mala se kenyelelitsoe lijong ho thibela kholo ea baktheria. Khaello ea setho e hlaha lintja le likatse, hangata feela ka lithibela-mafu. Ho ka etsahala hore boholo ba litlhokahalo tsa letsatsi le letsatsi tsa folate li kopana le ho qaptjoa ha baktheria ka maleng.

Litlhaloso le litemoso

Hoo e ka bang 50-95% ea folic acid e senngoa nakong ea ho pheha le ho boloka. Litholoana tsa khanya ea letsatsi le moea le tsona li kotsi ho folate. Boloka lijo tse nang le folate haholo ka har'a setshelo se lefifi se nang le mocheso.

Lipontšo tsa khaello ea folate

Ho haella ha folic acid feela ho etsahala seoelo 'me hangata ho amahanngoa le bofokoli bo bong ba limatlafatsi ka lebaka la khaello ea phepo e nepahetseng kapa mathata a ho monya. Matšoao hangata ke bofokoli, bothata ba ho tsepamisa mohopolo, ho teneha kapele, ho otla ha pelo le ho hema kapele. Ntle le moo, ho ka ba le bohloko le liso lelemeng; mathata a letlalo, moriri, manala; mathata ka pampitšaneng ea meno; maemo a phahameng a homocysteine ​​maling.

Matšoao a vithamine B9 e fetelletseng

Ka kakaretso, ho ja haholo ha ho na litla-morao. Maemong a sa tloaelehang, litekanyetso tse phahameng haholo tsa folate li ka lematsa liphio le ho baka tahlehelo ea takatso ea lijo. Ho nka vithamine B9 e ngata ho ka pata khaello ea vithamine B12. Tekanyo e phahameng ea letsatsi le letsatsi ea motho e moholo ke 1 mg.

Meriana e meng e ama ho noa vithamine B9 'meleng, har'a tsona:

• lithibela-pelehi tsa molomo;
• methotrexate (e sebelisetsoang ho phekola mofetše le mafu a itšireletsang mafung);
• lithethefatsi antiepileptic (phenytoin, carbamazepine, valproate);
• sulfasalazine (e sebelisetsoang ho alafa ulcerative colitis).

Bala hape ka livithamini tse ling: