Li-GMO li boetse li le moferefereng ka mor'a ho hatisoa ha thuto ke Moprofesa Gilles-Eric Séralini ka September 19, 2012, e bontšang phello ea ho sebelisoa ha poone e sa tloaelehang ho likhoto. Lebaka le letle la ho lekola bonnete ba boemo le litlamorao tse ka bang teng tsa liphatsa tsa lefutso bophelong ba rona.

Likokoana-hloko tse fetotsoeng ka liphatsa tsa lefutso, kapa li-GMO, li diphoofotsoana tseo DNA ya tsona e fetotsoeng ka ho kena lipakeng ha motho ka lebaka la boenjiniere ba liphatsa tsa lefutso (mekhoa ea baeloji ea limolek'hule e sebelisang liphatsa tsa lefutso ho sebelisa, ho ikatisa kapa ho fetola liphatsa tsa lefutso tsa lintho tse phelang). Ka hona mokhoa ona o etsa hore ho khonehe ho fetisetsa liphatsa tsa lefutso ho tloha nthong e phelang (phoofolo, semela, joalo-joalo) ho ea ho sebōpuoa se seng sa mofuta o mong. Joale re bua ka transgenic.