Lentsoe SIBO le emetse "ho hola ha baktheria ea mala a manyane" mme le bolela ho hola ho hoholo ha baktheria ea mala a manyane, a khetholloang ke palo e feteletseng ea libaktheria karolong ena ea mala le malabsorption. Lipontšo tse atileng haholo tsa kliniki ke letšollo, khase le matšoao a malabsorption. Lintho tse ka lebisang ho hola ha baktheria ke tsa anatomical (diverticulosis, blind loop, joalo-joalo) kapa ts'ebetso (litšitiso tsa ho tsamaea ha mala, ho ba sieo ha secretion ea asiti ea gastric). Kalafo e na le lijo tse nang le mafura a mangata, tse nang le lik'habohaedreite tse fokolang, taolo ea bofokoli, phekolo e pharaletseng ea lithibela-mafu, le ho felisa lintho tse tlatsetsang ho thibela ho khutla hape.

Lentsoe SIBO le emetse "ho hola ha baktheria ka maleng a manyane" kapa ho hola ha baktheria mala a manyane. E tšoauoa ka palo e feteletseng ea libaktheria ka maleng a manyane (> 105 / ml) e ka bakang mathata a malabsorption, ke hore, ho se monye ho lekaneng ha lijo.

Tlas'a maemo a tloaelehileng, karolo e haufi ea mala a manyane e na le libaktheria tse ka tlase ho 105 / ml, haholo libaktheria tsa aerobic Gram-positive. Boemo bona bo tlase ba baktheria bo bolokoa ke:

• phello ea li-contraction tse tloaelehileng tsa mala (kapa peristalsis);
• secretion e tloaelehileng ea asiti ea gastric;
• mucus;
• secretory immunoglobulins A;
• valve ea ileocecal e sebetsang.

Haeba baktheria e hola, ho na le libaktheria tse ngata tse fetang 105 / ml ka maleng a proximal. Sena se ka amahanngoa le:

• ho se tloaelehe kapa liphetoho tsa anatomical ka mpeng le / kapa mala a manyane (diverticulosis ea mala a manyane, loops ea ho buoa e foufetseng, maemo a post-gastrectomy, li-strictures kapa litšitiso tse sa fellang) tse khothalletsang ho fokotseha ha mala, ho lebisang ho hola ha baktheria; 
• mathata a tsamaiso ea tšilo ea lijo e amanang le lefu la tsoekere la neuropathy, scleroderma, amyloidosis, hypothyroidism kapa idiopathic intestinal pseudo-obstruction e ka fokotsang ho ntšoa ha baktheria;
• ho ba sieo ha secretion ea gastric acid (achlorhydria), e ka 'nang ea e-ba ea tlhaho ea lithethefatsi kapa ea ho buuoa.

Mefuta e atileng haholo ea libaktheria bakeng sa kholo ea baktheria ka maleng a manyane e kenyelletsa:

• Streptococcus sp;
• Bacteroides sp;
• Escherichia coli;
• staphylococcus sp;
• Klebsiella sp;
• le Lactobacillus.

Libaktheria tsena tse feteletseng li fokotsa matla a ho monya ha lisele tsa mala 'me li ja limatlafatsi, ho kenyeletsoa lik'habohaedreite le vithamine B12, e leng se ka fellang ka malabsorption ea lik'habohaedreite le khaello ea limatlafatsi le vithamine. Ho feta moo, libaktheria tsena li sebetsa ho letsoai la bile ka ho li fetola, li thibela ho thehoa ha li-micelles tse lebisang ho malabsorption ea lipids. Ho eketseha ho matla ha baktheria qetellong ho lebisa ho liso tsa mala a mala. 

Bakuli ba bangata ha ba na matšoao. Ntle le ho lahleheloa ke boima ba 'mele kapa khaello ea limatlafatsi le livithamine tse qhibilihang ka mafura (haholo-holo livithamini A le D), matšoao a tloaelehileng a kenyelletsa:

• bohloko ba mpeng;
• letšollo le matla ho feta kapa ka tlase;
• steatorrhea, ke hore, palo e phahameng ka ho sa tloaelehang ea lipids setulong, e bakoang ke malabsorption ea lipids le tšenyo ea lera la mucous;
• ho ruruha;
• khase e feteletseng, e bakoang ke likhase tse hlahisoang ke ho belisoa ha lik'habohaedreite.

Kalafo ea lithibela-mafu e tlameha ho etsoa, ​​eseng ho felisa limela tsa baktheria empa ho e fetola e le ho fumana ntlafatso ea matšoao. Ka lebaka la sebopeho sa polymicrobial ea limela tsa mala, lithibela-mafu tse pharaletseng lia hlokahala ho koahela libaktheria tsohle tsa aerobic le anaerobic.

Ka hona, kalafo ea SIBO e thehiloe ho nkeng, matsatsi a 10 ho isa ho a 14, ka molomo, e le 'ngoe kapa tse peli tsa lithibela-mafu tse latelang:

• Amoxicillin / clavulanic acid 500 mg makhetlo a 3 ka letsatsi;
• Cephalexin 250 mg makhetlo a 4 ka letsatsi;
• Trimethoprim / sulfamethoxazole 160 mg / 800 mg habeli ka letsatsi;
• Metronidazole 250 ho 500 mg makhetlo a 3 kapa a 4 ka letsatsi;
• Rifaximin 550 mg makhetlo a 3 ka letsatsi.

Kalafo ena e pharalletseng ea lithibela-mafu e ka fetoha cyclical kapa esita le ho fetoloa, haeba matšoao a atisa ho hlaha hape.

Ka nako e ts'oanang, lintlha tse khothalletsang ho ata ha baktheria (lintho tse sa tloaelehang tsa anatomical le ts'ebetso) li tlameha ho tlosoa 'me ho khothaletsoe phetoho ea lijo. Ka 'nete, libaktheria tse feteletseng haholo-holo li senya lik'habohaedreite ka har'a lumen ea mala ho e-na le lipids, lijo tse nang le mafura a mangata le fiber le lik'habohaedreite tse fokolang - lactose mahala - lia khothaletsoa. Khaello ea vithamine, haholo-holo vithamine B12, le eona e tlameha ho lokisoa.